If and when a photograph is taken of US Vice-President JD Vance standing next to Iran's Parliamentary Speaker Mohammad Bagher Ghalibaf in Islamabad this weekend, it will make history. That moment would mark the highest-level face-to-face talks between the Islamic Republic of Iran and the United States of America since the 1979 Islamic Revolution shattered their strong strategic bond and cast a long shadow which still darkens relations to this day. The two men may not smile. They may not even shake hands. It would not make this troubled relationship any more easy, any less hostile. But it would send a signal that both sides want to try to end a war sending shocks worldwide, avoid an even riskier escalation, and turn to diplomacy to do a deal. There's zero chance though of US President Donald Trump's optimistic prediction of a 'peace deal' within this shaky two-week ceasefire - its terms were contested and broken since the moment it was announced earlier this week. Even until the eleventh hour, Iranians kept everyone guessing over whether they would still show up while Israel was insisting there would be no ceasefire in Lebanon. But if serious and sustained talks make a start, it would also mark the most significant push since Trump pulled out of the previous landmark nuclear deal in 2018, during his first term. Those talks, in endless rounds stretching over nearly 18 months of breakthroughs and breakdowns, were the last high-level meetings between the then-US Secretary of State John Kerry and Iran's then-Foreign Minister Mohammad Javad Zarif. Efforts since then, including during US President Joe Biden's term, made little headway. Ali Vaez of the International Crisis Group notes that the dispatch of more senior officials and high stakes of failure for all sides could open possibilities that weren't there before. However, he cautions that this time is still 'exponentially harder'. The gaps between the two sides remain very wide and the distrust runs very deep. That well is especially vast for Tehran after their last two series of negotiations were suddenly affected by the opening salvos of a US-Israeli war. When they do talk, their negotiating styles are poles apart. Iran insists on raising the level of engagement, specifically to Vance. Iranian hardliners are calling for a cautious approach to these negotiations, which they have tied up with concerns about their missile programs and regional influence following the recent hostilities. As the talks commence, the world watches with cautious optimism, knowing well the history that complicates these crucial discussions.