Nobel Prize-winning American scientist James Watson, one of the co-discoverers of the structure of DNA, has died aged 97.

In one of the greatest breakthroughs of the 20th Century, he identified the double-helix structure of DNA in 1953 alongside British scientist Francis Crick, setting the stage for rapid advances in molecular biology.

However, Watson's reputation and standing were significantly damaged by his controversial comments about race and intelligence. He suggested a genetic connection to differences in IQ between races during a televised interview.

His passing was confirmed by Cold Spring Harbor Laboratory, where he spent decades researching, before stepping down from his role as chancellor due to his comments.

Watson shared the Nobel Prize in 1962 with Maurice Wilkins and Francis Crick for their discovery of DNA's double helix structure. We have discovered the secret of life, they proclaimed at the time.

By the early 2000s, Watson found himself largely alienated from the scientific community due to his remarks on race and gender.

In 2007, he expressed a bleak outlook regarding Africa, suggesting a discrepancy in intelligence, which led to his dismissal from leadership roles at Cold Spring Harbor Laboratory.

Despite his significant contributions to science, Watson faced strong backlash as his views were labeled as reprehensible and lacking scientific support.

James Watson was born in Chicago in April 1928 and displayed early academic promise, winning a scholarship to the University of Chicago at age 15. His interest in molecular biology led him to Cambridge University, where he met Crick. Together, they constructed models of DNA, aided by Rosalind Franklin's critical data.

Watson later held a professorship at Harvard University and transformed Cold Spring Harbor Laboratory into a leading scientific institute. He even became the first living Nobel laureate to auction his medal, which sold for $4.8 million in 2014, reflecting his feelings of ostracism from the scientific community.

Watson's legacy remains mixed: celebrated for his groundbreaking work on DNA yet condemned for his outspoken and controversial views on race.